Category Archives: Uncatagorized

MS and Stem Cell Particles

A picture of me.

Bill Walker                                                                   

This is a reprint from a recent study:

Dr. Metcalfe, who is based at Cambridge University in England, is currently looking for funding to further develop her theory that using a stem cell particle called a LIF would switch off the body’s auto-immune cells and help repair the brain.

In addition to being able to switch off the body’s autoimmune response, LIF also protects the brain and spinal cord — the areas affected by multiple sclerosis — and aids in repairing tissue, including brain tissue.

The research has not been smooth sailing. Metcalfe has found that LIF cannot survive outside the cell for more than 20 minutes before being broken down by the body, making it difficult to use as a therapy. However, she has found that nanoparticles could be the answer to the problem, as they can be used to help deliver the LIF therapy. By using antibodies with the nanoparticles, the therapy can be directed to certain areas of the brain — helping to repair damage caused by multiple sclerosis.

Metcalfe is now looking for research funding and hopes that one of the big pharmaceutical companies will step in. She hopes to begin clinical trials of the therapy by 2020.

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MS and Gut Bacteria

A picture of me.

Bill Walker

This is a reprint from a recent study.

A study has found that microbes in your gut may influence the progression of multiple sclerosis (MS). It could be a key step towards specific treatment, and help solve what causes MS.

Published in the Proceedings of the National Academy of Sciences, two different teams conducted separate research and made the same findings. One was from the University of California, San Francisco, and the other from the Max Planck Institute in Germany.

The first team investigated the gut microbiomes of 71 MS patients and 71 control subjects. They identified specific species of bacteria that were more common in the former than the latter. Next, they exposed these bacteria to human immune cells, and found that two species triggered cells to become pro-inflammatory. One found at lower levels triggered immune responses.

In tests on mice, they found that these bacteria had a similar effect. Replacing mice microbiomes with those from an MS patient caused the mice to lose immune-regulatory cells and develop neurodegeneration, a pathway to MS.

The second study came to a similar conclusion, finding that microbiome transplants could increase symptoms in mice.

“Two different groups, using two separate cohorts of patients and controls, and two distinct mouse models of the disease, saw very similar results,” Egle Cekanaviciute said in a statement, who was involved in both studies. “This is very promising evidence that we’re on the right track.”

MS affects about 2.5 million people across the globe, and is known as an autoimmune neurodegenerative disorder. It can lead to loss of vision, weakness, and even paralysis. It’s caused by the immune system attacking the insulation around nerve cells, called myelin, but scientists have been at a loss to explain why this occurs.

These latest studies could provide an answer. While the microbiome probably isn’t the only trigger, it could play a role. This could lead to some new treatments in the future to help tackle MS.

“The microbiome is very malleable,” said Sergio Baranzini, also involved in both studies. “You could relatively easily change it in an adult who has MS or is susceptible – something you cannot do with their genetics. This is not a magical approach, but it is hopeful.”

MS a Child with Cancer and a Kitten

A picture of me.

Bill Walker

The power of having a pet, in this case a kitten, can change people’s lives forever. The following true short story was published in Parade Magazine a few weeks ago. And though it is not about multiple sclerosis it is nothing but pure love, so I decided to share it here. It brings hope that any disease can be cured!

 

ONE LAST WISH

 

Robin and Mark Myers, of Suwanne, GA., are grateful for the rescue that came into their family’s life when their 12-year-old daughter, Kylie, was battling cancer.

     “Cancer stole a lot from Kylie, but she was determined it wouldn’t steal her joy,” says Robin. When the family got the news that Kylie was dying. She looked up with a weak smile and a twinkle in her eye, asking her dad, “Now can I finally have a kitten?” Sharing their story on what would have been Kylie’s 15th birthday, Robin recalls, “We would’ve said yes to anything.”

     A friend swung by the local shelter and rushed to Kylie’s bedside with a kitten. Kylie named her Liza and the kitten curled up in the crook of her arm. “Liza just stayed there and didn’t leave her side at all in the few days until we lost Kylie,” Robin recalls through tears. “The last thing Kylie said was, ‘I want you to help find a cure for childhood cancer, and please take care of my kitty.’

     “But it’s Liza, who takes care of me, “says Robin. “When I cry, Liza comes running. She has an uncanny understanding. She rescued our family and keeps Kylie’s spirit alive.” (Visit Parade Magazines website for a video. Sorry, many sites that I publish on will not permit links.)

    

     (The FDA just approved a way to enhance the body’s own immune system to attack, Lymphoma, a form of blood cancer, which has been effective in curing 85% of the patients that have received this new breakthrough treatment. It is hoped that this treatment can one day soon be developed for use in all types of cancers for both humans and pets as well. Making cancer a disease of the past!)

 

Please support your local shelter and adopt whenever you can. And always get your pets spay or neutered.

Bill Walker

MS Turmeric and Inflammation

A picture of me.

That would be me!

     Turmeric is derived from the spice curry used extensively in India. It’s health benefits range from helping to treat constipation to also being a huge anti-inflammatory agent. I personally had read so many great things about turmeric , including that some people believed it have something to do with India’s very small incidence of Multiple Sclerosis, that I just had to give it a try. 

     That was over a year ago and unfortunately I did not experience the health benefits that I had hoped to achieve. I am certainly not saying that it doesn’t provide benefits to other people but it doesn’t seem to do much for me except cost money. It may come down to each persons own body chemistry being a factor in whether turmeric has a positive effect or not. I know that researchers are discovering that many cancer drugs can work wonders for some people and have absolutely little if any effect for others.

     In closing, if it works for you, by all means keep using it as long as your neurologist and general practitioner are aware of you using it as many supplements like turmeric can have undesirable effects when used with other prescribed drugs!   

by

Bill Walker

 

PS. I am still in search of a literary agent/publisher for my book if anyone can help by putting in a good word for me!

MS Donald Trump and His Medicaid Budget Cuts

A picture of me.

That would be me!

No matter how you voted or what your personal political beliefs are of Donald Trump and his administration, the 2017-2018 budget that was just released, is nothing short of draconian with respect to anyone who has a disability.

This budget calls for cuts of up to 1.4 Trillion, yes Trillion, dollars to medicaid over the next ten years. This will mean every single person with a disability that relies on medicaid for health care, including children, will be impacted.

Donald Trump has also asked for cuts of hundreds of millions of dollars from the social security fund that provides disability checks for both Veterans and people living with disabilities. And, on top of that, his administration is also seeking large cuts to the Snap program that helps people with disabilities buy food through the use of food stamps to help supplement their disability checks.  

People with disabilities need to stand as one and say, “NO!” to these outrages cuts.

Bill Walker

MS Halloween and Chocolate

Fred Meyer Holiday Pumpkin Patch

Yea, not very scary! LOL

As we rapidly approach Halloween, probably the second biggest holiday where chocolate is indulged upon with Valentines Day being the first, I once again broach the subject of a few of chocolates healthy benefits. I’ve already discussed how chocolate is a huge anti-inflammatory treat as long as you eat the purer forms of chocolate with higher amounts of cocoa then the regular milk chocolate that is mostly available in grocery stores candy counters. And as long as you eat it remembering that moderation is the key here. And also remembering that chocolate, no matter what kind you eat, also has a high fat content that can make weight gain a real possibility if you consume to much.

I also wanted to add information that is new about a study using athletes. This study found that athletes who consumed small amounts of dark chocolate with a high cocoa content once a week of about 1.4 ounces just before working out found that their endurance was greatly enhanced. It appears that this rich chocolate acts to open veins and arteries allowing for greater blood flow which increases stamina. And if it helps athletes with their workouts I don’t see any reason that dark chocolate wouldn’t also help people with other diseases or disorders do the same thing during their exercise workouts including people with multiple sclerosis.

So please enjoy your Halloween and allow yourself a small indulgence without guilt as you celebrate All Hallows Day. The day we all chase away all of those negative spirits from our past. Be safe, and please, try to enjoy yourselves as we begin a long march towards the Fall and Winter Holidays to come!

And now I have a small favor to ask of anyone who might have either an Editor at a Book Publishing House or a Literary Agent in the family or as a friend. I’m trying to find either an Editor or an Agent that would give my book VISUS a serious read with the hopes of getting  my book out into the literary hands of the general public. Even if you get them to read the first chapter that is listed above in the title bar would be greatly appreciated by me.

Again, please have a safe Halloween weekend and enjoy your family and friends!

Bill Walker

The Burlington Washington Shootings

Mountains at sunsetYesterday five people were shot to death and one sent to the hospital with critical injuries in a senseless act of violence that is also occurring all around the world even as I write this. However this one is way to close to home for me. You see I used to work at the Burlington Mall just a few years ago and just down the corridor from Macy’s!

The questions that come to mind in a tragedy like this are hard to articulate and accept. What, if anything, can be done to stop the killing? With each act of violence people become more desensitized to these horrible acts of insanity and violence. And one only has to watch the nightly news to be barraged with a litany of human suffering that is mostly, and unbelievably, self inflicted.

I have Multiple Sclerosis, and believe it or not, it’s easier to blame God, even though I realize that it’s not Gods fault, for a disease that has taught me understanding and compassion. These are precious gifts even if learned through hardship and pain. But I find that I just have a really hard time finding any understanding in acts of violence that take another life in most cases.

Where do we go, and where do we turn from here? Or are we doomed to a fate filled existence of hate without end?

Prayers for both the living, and the dead. And may we all see the light of a truly blessed and harmonious world that we could create if we only took the time  to realize that Heaven on Earth is a possibility that is not beyond imagination to conceive. It just takes a little effort and a long heartfelt look at human ego and how to build a loving soul rather than a hate filled one!

Bill Walker